Integrity Testing

At the factory, each Planova filter is evaluated with two integrity tests.
The New Pressure Hold (NPrH) Test, developed by Asahi Kasei Medical Co., Ltd., validates pore size distribution by nitrogen gas flow rate. The leakage test verifies the absence of larger fiber defects (pinholes).

Users can perform the leakage test for large-defect testing and the high-precision Asahi Gold Particle Test (AGPT) for pore size distribution testing. The leakage test is conducted before and after use to confirm that the Planova filter is free from pinholes or large defects. The unique AGPT is performed after use to confirm that pore size distribution has not changed inappropriately over the course of the filtration.

The leakage test is based on detection of pressurized air bubbling through the filter’s fibers. This test provides a reliable and precise indication of filter membrane quality, both before and after filter use.

The leakage test can be performed manually as a visual test, or automatically using the Planova Leak Tester (PLT-AM10), which measures airflow through the filter’s hollow fibers. The Planova Leak Tester can be used with 4.0 m², 1.0 m², 0.3 m² and 0.12 m² filters. A touch panel display allows easy operation and readout. Test results can also be printed out.

The unique Asahi Gold Particle Test (AGPT) is the most precise user-conducted integrity test on the market. It serves to reconfirm filter quality (pore size distribution) after filtration.

In the test, an Asahi Gold Particle (AGP) solution of colloidal gold particles, similar in size to the target viruses, is introduced into the filter.

AGP solution kits are available to match specific Planova filters. The AGP-HA15, AGP-HA20 and AGP-HA35 are for Planova 15N, 20N and 35N filters, respectively; the AGP-EX is for Planova BioEX filters.

The automated and validated Asahi Gold Particle Test System (AGPTS) is also available.

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