Flow-Through Mode
Even when operating under a wide variety of conditions during biopharmaceutical manufacturing processes, QyuSpeed D demonstrates both a high target protein recovery rate and an excellent capacity for impurity removal.
Pre-Protein A Chromatography Use
Pre-protein A chromatography protein solutions were processed with QyuSpeed D. IgG recovery and HCP removal were measured in the filtrates.
Composition of Sample Protein Solutions
IgG: 1 mg/mL
HCP: 0.2 mg/mL
NaCl: 0.1 M
Buffer: 20 mM Tris-HCl (pH 7.5）
Post-Protein A Chromatography Use
Post-protein A chromatography protein solutions were processed with QyuSpeed D. IgG recovery and HCP removal were measured in the filtrates.
Composition of Sample Protein Solutions
IgG: 1 mg/mL
HCP: 0.1 mg/mL
NaCl: 0 M
Buffer: 20 mM Tris-HCl + 10 mM Citrate + 10mM Phosphate (pH 7.0)
Post-Cation Exchange Chromatography Use
Post-cation exchange chromatography protein solutions were processed with QyuSpeed D. IgG recovery and HCP removal were measured in the filtrates.
Composition of Sample Protein Solutions
IgG: 1 mg/mL
HCP: 0.1 mg/mL
NaCl: 0.15 M
Buffer: 20 mM Tris-HCl + 10 mM Acetate (pH 6.0）