Large Volume Processing
A key feature of BioOptimal MF-SL is its ability to quickly process large volumes of feed solution. Compared to other existing microfilters, BioOptimal MF-SL can process the largest volume of solution in the shortest amount of time.
Filtration Volume vs. Filtration Time
Experiment processed a suspension of CHO cells with
Cell Density: 1.2 x 107 cells/mL, Viability: 99.4%, Turbidity: 872 NTU
Stable Filtration Performance
Unlike other microfilters, BioOptimal MF-SL's unique membrane structure and tangential flow filtration mode allow it to provide a consistently low TMP despite increases in filtration volume.
This low TMP results in a reliably high target protein recovery rate.
TMP vs. Filtration Volume
Experiment processed a suspension of CHO cells with
Cell Density: 1.2 x 107 cells/mL, Viability: 99.4%, Turbidity: 872 NTU
High Protein Recovery Rate
BioOptimal MF-SL achieves high recovery rates of target proteins. The graph below, which illustrates the before and after of a BioOptimal MF-SL filtration, shows a filtrate with a 92% recovery rate of the IgG originally spiked into the CHO cell feed solution.
IgG Quantity Before and After Filtration
